Roberto Giacomelli Selected Research

Adult-Onset Still's Disease

7/2022	Expanding the spectrum of the hyperferritinemic syndrome, from pathogenic mechanisms to clinical observations, and therapeutic implications.
4/2022	Cytokine profile, ferritin, and multi-visceral involvement characterise macrophage activation syndrome during adult-onset Still's disease.
2/2022	The hyper-expression of NLRP4 characterizes the occurrence of macrophage activation syndrome assessing STING pathway in adult-onset Still's disease.
3/2021	The Pathogenic Role of Interferons in the Hyperinflammatory Response on Adult-Onset Still's Disease and Macrophage Activation Syndrome: Paving the Way towards New Therapeutic Targets.
1/2021	The treatment of adult-onset Still's disease with anakinra, a recombinant human IL-1 receptor antagonist: a systematic review of literature.
1/2020	Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort.
1/2020	Comparison of Early vs. Delayed Anakinra Treatment in Patients With Adult Onset Still's Disease and Effect on Clinical and Laboratory Outcomes.
1/2020	Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort.
1/2020	The reduction of concomitant glucocorticoids dosage following treatment with IL-1 receptor antagonist in adult onset Still's disease. A systematic review and meta-analysis of observational studies.
4/2019	Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study.

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Roberto Giacomelli Research Topics

Disease

23	Systemic Scleroderma (Systemic Sclerosis) 10/2022 - 01/2002
23	Rheumatoid Arthritis 03/2021 - 02/2007
16	Adult-Onset Still's Disease 07/2022 - 01/2014
13	Fibrosis (Cirrhosis) 12/2019 - 01/2011
12	Inflammation (Inflammations) 10/2022 - 06/2007
10	COVID-19 07/2022 - 01/2020
10	Rheumatic Diseases (Rheumatism) 01/2022 - 03/2014
9	Arthritis (Polyarthritis) 10/2021 - 08/2009
9	Psoriatic Arthritis 01/2021 - 03/2013
8	Macrophage Activation Syndrome 10/2022 - 05/2015
7	Lymphoma (Lymphomas) 01/2022 - 06/2014
7	Autoimmune Diseases (Autoimmune Disease) 02/2021 - 05/2013
6	Type 2 Diabetes Mellitus (MODY) 03/2021 - 06/2015
6	Infections 01/2021 - 12/2012
5	Fever (Fevers) 10/2022 - 12/2016
5	Fatigue 07/2022 - 01/2019
5	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021 - 03/2013
5	Hypertension (High Blood Pressure) 12/2020 - 01/2017
5	Lymphadenopathy 01/2020 - 12/2016
4	Exanthema (Rash) 10/2022 - 12/2016
4	Pain (Aches) 07/2022 - 02/2007
4	Insulin Resistance 01/2021 - 04/2018
4	Necrosis 12/2020 - 02/2007
4	Atherosclerosis 01/2019 - 06/2007
3	Chronic Disease (Chronic Diseases) 07/2022 - 01/2021
3	Spontaneous Abortion (Miscarriage) 03/2006 - 09/2003
2	Abdominal Pain (Pain, Abdominal) 10/2022 - 01/2020
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2022 - 01/2018
2	Hyperferritinemia 07/2022 - 01/2020
2	Cytokine Release Syndrome 07/2022 - 04/2022
2	Sjogren's Syndrome (Sjogren Syndrome) 01/2022 - 05/2013
2	Serositis 01/2022 - 12/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2021
2	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2021 - 07/2014
2	Sialadenitis 01/2021 - 11/2016
2	Leukopenia 01/2021 - 06/2014
2	Cryoglobulinemia 01/2021 - 01/2017
2	Proteinuria 01/2021 - 01/2020
2	autosomal dominant familial Periodic fever 01/2021 - 01/2020
2	Neoplasms (Cancer) 01/2021 - 08/2019
2	Purpura 01/2021 - 11/2015
2	Fibromyalgia (Fibrositis) 11/2020 - 01/2019
2	Vasculitis (Vasculitides) 01/2020 - 06/2014
2	Amyloidosis 01/2020 - 01/2020
2	Pulmonary Arterial Hypertension 01/2020 - 01/2011
2	Ankylosing Spondylitis 12/2018 - 01/2016

Drug/Important Bio-Agent (IBA)

17	CytokinesIBA 07/2022 - 09/2003
10	Ferritins (Ferritin)IBA 10/2022 - 05/2015
9	Biomarkers (Surrogate Marker)IBA 10/2022 - 06/2014
9	AntibodiesIBA 07/2022 - 10/2004
9	Biological ProductsIBA 03/2021 - 06/2015
8	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2022 - 04/2018
8	Interleukin-1 (Interleukin 1)IBA 01/2022 - 06/2015
7	Antirheumatic Agents (DMARD)IBA 01/2022 - 12/2012
7	C-Reactive ProteinIBA 01/2022 - 02/2007
7	Pharmaceutical PreparationsIBA 03/2021 - 03/2014
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2019 - 02/2007
6	InterleukinsIBA 01/2022 - 01/2015
5	GlucocorticoidsIBA 01/2022 - 01/2020
5	SteroidsIBA 01/2022 - 12/2012
5	Tumor Necrosis Factor InhibitorsIBA 03/2021 - 06/2016
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2002
5	EnzymesIBA 05/2020 - 05/2015
4	tocilizumab (atlizumab)FDA Link 01/2022 - 01/2014
4	Rheumatoid FactorIBA 02/2021 - 11/2015
4	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2017
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 07/2015
3	Interleukin-10 (Interleukin 10)IBA 04/2022 - 07/2019
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 01/2019
3	Colchicine FDA LinkGeneric 01/2022 - 01/2020
3	Oxygen (Dioxygen)IBA 01/2022 - 08/2011
3	Rituximab (Mabthera)FDA Link 12/2021 - 05/2013
3	CollagenIBA 01/2021 - 06/2013
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2021 - 01/2019
3	Vitamin D FDA LinkGeneric 12/2020 - 01/2018
3	AutoantibodiesIBA 01/2020 - 08/2009
3	Etanercept (Enbrel)FDA Link 01/2020 - 02/2007
3	Proteins (Proteins, Gene)FDA Link 08/2019 - 08/2015
3	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2019 - 06/2016
3	MicroRNAs (MicroRNA)IBA 01/2019 - 10/2018
3	CryoglobulinsIBA 01/2017 - 06/2014
2	ametantrone (HAQ)IBA 07/2022 - 02/2007
2	Phospholipids (Phosphatides)FDA LinkGeneric 07/2022 - 04/2018
2	InterferonsIBA 02/2022 - 03/2021
2	tofacitinibIBA 01/2022 - 01/2021
2	Immunologic Factors (Immunomodulators)IBA 01/2022 - 01/2021
2	ChemokinesIBA 02/2021 - 03/2012
2	Insulin (Novolin)FDA Link 01/2021 - 01/2021
2	Interleukin-17 (Interleukin 17)IBA 01/2021 - 01/2018
2	Complement System Proteins (Complement)IBA 01/2021 - 03/2013
2	Certolizumab Pegol FDA Link 11/2020 - 01/2020
2	golimumab FDA Link 01/2020 - 07/2017
2	Imatinib Mesylate (Gleevec)FDA Link 01/2020 - 07/2014
2	AdipokinesIBA 02/2019 - 01/2018

Therapy/Procedure

24	Therapeutics 07/2022 - 01/2002
4	Immunomodulation 01/2022 - 03/2013
3	Stem Cell Transplantation 11/2020 - 05/2013
3	Drug Therapy (Chemotherapy) 05/2020 - 05/2013
3	Biological Therapy 02/2017 - 08/2011
2	Hyperbaric Oxygenation 11/2020 - 01/2019